
San Francisco, CA 94107
Unlock a rare development opportunity in the heart of Potrero Hill with this vacant duplex at 2109-2111 22nd Street. Perfectly positioned in one of San Francisco’s most coveted neighborhoods, this property features two charming "mini-residences" offering immediate versatility: a light-filled top-floor unit with a private deck and a lower-level retreat leading to an expansive patio. Situated on a deep lot, the site serves as a blank canvas for a visionary expansion or a lush urban garden sanctuary. The location is a commuter’s dream with seamless freeway access and close proximity to Zuckerberg San Francisco General, UCSF Mission Bay, and the convenience of Whole Foods just blocks away. Add this duplex to your portfolio and take advantage of city’s current red hot rental market, or develop the property to maximize its potential in one of San Francisco’s coolest neighborhoods Potrero Hill.
Property is extensive renovation needed.
Built in 1946 and marketed primarily as a 'development opportunity,' this property features a highly dated kitchen and basic bathrooms that exceed the 30-year renovation threshold. The small square footage and 'blank canvas' description suggest the structure requires a total rehab or expansion to meet modern living standards.
Elementary School: Chinese Immersion School At Deavila (9/10). Middle School: Lilienthal (Claire) Elementary School (9/10). High School: Lowell High School (10/10).
Situated in one of San Francisco’s most desirable neighborhoods, the property offers exceptional proximity to UCSF Mission Bay, Zuckerberg SF General, and major commuter freeways.
Delivered vacant on a deep lot, this property serves as a rare blank canvas for a visionary expansion or a complete redevelopment to maximize value in a high-demand market.
At only 752 total square feet for two units, the living spaces are exceptionally small, which may necessitate immediate expansion to attract premium rental rates or long-term tenants.
Several of the immediate neighborhood public schools carry very low performance ratings (1/10 and 2/10), which could be a drawback for future resale to families.
No exterior & parking available.
Grades K-5 • 0.3 mi
Grades K-5 • 0.4 mi
Grades K-5 • 0.4 mi
No sensitive facilities data found.
| Feature | Subject | Average Home |
|---|---|---|
| Beds | 0.0 | 4.6 |
| Baths | 0.0 | 4.0 |
| Square foot | 752 | 3,221.149 |
| Lot Size | 1,873 | 2,766.255 |
| Price | $850.0K | $2.13M |
| Price per sq ft | $1.1K | $697 |
| Built year | 1946 | 1925 |
| HOA | $0 | $0 |
| Days on market | 164 | 53 |
May 13, 2026
$850,000
Initial Listing
Oct 17, 2019
$1,048,000
Public Record
Apr 29, 2016
$850,000
Public Record
Jun 10, 2002
$355,000
Public Record